anti hif prolyl hydroxylases polyclonal primary antibodies

Description: Anti-PHD2 / prolyl hydroxylase antibody (ab226755) AbcamCatalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF-1 alpha at 'Pro-402' and 'Pro-564', and HIF-2 alpha. Functions as a cellular oxygen sensor and, under normoxic conditions, targets HIF through the hydroxylation for proteasomal degradati ...

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(PDF) Potent and Selective Triazole-Based Inhibitors of anti hif prolyl hydroxylases polyclonal primary antibodies

Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain Article (PDF Available) in PLoS ONE 10(7):e0132004 July 2015 anti hif prolyl hydroxylases polyclonal primary antibodies(ab4561) Anti-PHD2 / prolyl hydroxylase antibody - Abcam anti hif prolyl hydroxylases polyclonal primary antibodiesThe LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity. In Nature Cell Biology on 1 February 2012 by Foxler, D. E., Bridge, K. S., et al.. Applications:

(ab4561) Anti-PHD2 / prolyl hydroxylase antibody - Abcam anti hif prolyl hydroxylases polyclonal primary antibodies

The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity. In Nature Cell Biology on 1 February 2012 by Foxler, D. E., Bridge, K. S., et al.. Applications:A Zebrash Model to Study and Therapeutically HIF prolyl hydroxylases belong to the 2OG-dependent dioxygenase superfamily (13), which also require molecular anti hif prolyl hydroxylases polyclonal primary antibodies the primary antibodies mouse monoclonal anti-PCNA (1:1,000; Abcam), rabbit polyclonal anti-HIF-1a anti hif prolyl hydroxylases polyclonal primary antibodies Abcam), rabbit polyclonal anti-HIF-1a (1:100; ref. 28) and rabbit polyclonal anti-GFP (1:250; Torrey PinesBiolabs)wereused anti hif prolyl hydroxylases polyclonal primary antibodiesActivation of the HIF Prolyl Hydroxylase by the Iron anti hif prolyl hydroxylases polyclonal primary antibodiesNov 02, 2011Berra E, Benizri E, Ginouvès A, Volmat V, Roux D, Pouysségur J. HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia. EMBO J. 2003; 22:40824090. [PMC free article] Bruick RK, McKnight SL. A conserved family of prolyl-4-hydroxylases that modify HIF. Science. 2001; 294:13371340.

Activation of the HIF Prolyl Hydroxylase by the Iron anti hif prolyl hydroxylases polyclonal primary antibodies

Nov 02, 2011Three HIF prolyl hydroxylases anti hif prolyl hydroxylases polyclonal primary antibodies were used for HIF and CREB western blots. Membranes were probed using mouse anti-HIF1 (Transduction, 1:1000) or mouse anti-CREB (Cell Signaling, 1:1000) antibodies. For detection of hydroxylated HIF1, A549 cells were treated with 100 M MG132 for 6 hr followed by 25 M DFO for 2 hr. Nuclear extracts (40 anti hif prolyl hydroxylases polyclonal primary antibodiesActivation of the HIF Prolyl Hydroxylase by the Iron anti hif prolyl hydroxylases polyclonal primary antibodiesNov 02, 2011Three HIF prolyl hydroxylases anti hif prolyl hydroxylases polyclonal primary antibodies were used for HIF and CREB western blots. Membranes were probed using mouse anti-HIF1 (Transduction, 1:1000) or mouse anti-CREB (Cell Signaling, 1:1000) antibodies. For detection of hydroxylated HIF1, A549 cells were treated with 100 M MG132 for 6 hr followed by 25 M DFO for 2 hr. Nuclear extracts (40 anti hif prolyl hydroxylases polyclonal primary antibodiesAnti-HIF Prolyl Hydroxylase Antibody Products BiocompareCompare Anti-HIF Prolyl Hydroxylase Antibody Products from leading suppliers on Biocompare. View specifications, prices, citations, reviews, and more.

Anti-HIF-1 beta Antibodies Invitrogen

HIF-1 is a heterodimer composed of HIF-1 alpha and HIF-1 beta subunits. Both subunits are constantly translated. However, under normoxic conditions, human HIF-1 alpha is hydroxylated at Pro402 or Pro564 by a set of HIF prolyl hydroxylases, is polyubiquinated, and eventually degraded in proteosomes.Anti-HIF-1-alpha Antibody, hydroxyproline (Pro402) 07-1585Use Anti-HIF-1-alpha Antibody, hydroxyproline (Pro402) (Rabbit Polyclonal Antibody) validated in WB to detect HIF-1-alpha also known as Hypoxia-inducible factor 1-alpha, HIF1-alpha. - Find MSDS or SDS, a COA, data sheets and more information.Anti-PHD1 Antibodies InvitrogenPHD1 Antibodies . Prolyl hydroxylase domain proteins HIF PHD1, HIF PHD2 and HIF PHD3 (known as PHD1, PHD2 and PHD3 in rodents, respectively) can hydroxylate HIF-alpha subunits. Hypoxia-inducible factor (HIF) is a transcriptional regulator important in several aspects of oxygen homeostasis.

Anti-PHD2 / prolyl hydroxylase antibody (ab226755) Abcam

Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF-1 alpha at 'Pro-402' and 'Pro-564', and HIF-2 alpha. Functions as a cellular oxygen sensor and, under normoxic conditions, targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau anti hif prolyl hydroxylases polyclonal primary antibodiesDiscovery and Preclinical Characterization of factors hypoxia-inducible factor (HIF) 1a and HIF2a control the physiologic response to hypoxia and invoke a program of increased erythropoiesis. Levels of HIFa are modulated by oxygen tension via the action of a family of HIF-prolyl hydrox-ylases (PHDs), which tag HIFa for proteasomal degradation.EGLN1/PHD2 Antibody (NB100-2219) Novus BiologicalsRabbit Polyclonal Anti-EGLN1/PHD2 Antibody cited in 32 publications. Validated WB, ICC/IF, IHC, IHC-P, IP, KD, KO. anti hif prolyl hydroxylases polyclonal primary antibodies Primary Antibodies are guaranteed for 1 year from date of anti hif prolyl hydroxylases polyclonal primary antibodies Kuvaja P et al. Systemic long-term inactivation of hypoxia-inducible factor prolyl 4-hydroxylase 2 ameliorates aging-induced changes in mice without affecting their anti hif prolyl hydroxylases polyclonal primary antibodies

EGLN3/PHD3 Antibody (NB100-139) Novus Biologicals

Peroxisomal localization of hypoxia-inducible factors and hypoxia-inducible factor regulatory hydroxylases in primary rat hepatocytes exposed to hypoxia-reoxygenation. Am J Pathol. 2006 Oct [PMID 17003483] (WB, IHC-P, ICC/IF, EM, Rat) WB, IHC-P, ICC/IF, EM Rat Li N et al. Expression actions of HIF prolyl-4-hydroxylase in the rat kidneys.HIF1 interacts with Kindlin2 and influences breast anti hif prolyl hydroxylases polyclonal primary antibodiesThe primary antibodies used for western blot are antiHIF1 human monoclonal antibody (Affinity, BF0593, USA), antiKindlin2 rabbit polyclonal antibody (Sigma, K3269, USA), antipFAK rabbit monoclonal antibody (Abcam, ab4792, UK), and antiP4HA1 rabbit monoclonal antibody (Proteintech, 126581AP, China).Human/Mouse/Rat HIF-2 alpha /EPAS1 Antibody AF2997 Detection of Human, Mouse, and Rat HIF2 alpha /EPAS1 by Western Blot. Western blot shows lysates of MCF-7 human breast cancer cell line, bEnd.3 mouse endothelioma cell line, and PC-12 rat adrenal pheochromocytoma cell line untreated (-) or treated (+) with 150 µM CoCl 2 for 16 hours. PVDF Membrane was probed with 1 µg/mL of Goat Anti-Mouse HIF-2a/EPAS1 Antigen Affinity-purified Polyclonal anti hif prolyl hydroxylases polyclonal primary antibodies

Hyperglycemia Regulates Hypoxia-Inducible Factor-1 anti hif prolyl hydroxylases polyclonal primary antibodies

The membrane was incubated with antiHIF-1 primary antibody (monoclonal antibody or antiHIF-1 antiserum) in a 1:500 dilution in PBS that contained 1% nonfat milk for 2 h. After several washes, the membrane was incubated with the secondary peroxidase-conjugate antibody (1:750) diluted in PBS that contained 1% nonfat milk for 1.5 h.Hypoxia-inducible Factors in the First Trimester Human anti hif prolyl hydroxylases polyclonal primary antibodiesLung development takes place in a relatively low-oxygen environment, which is beneficial for lung organogenesis, including vascular development. Hypoxia-inducible factor (HIF)-1 plays an important anti hif prolyl hydroxylases polyclonal primary antibodiesImages of Anti Hif Prolyl hydroxylase Polyclonal Primary antib imagesAnti Prolyl Hydroxylase 1 Antibody (PrecisionAb Polyclonal anti hif prolyl hydroxylases polyclonal primary antibodiesRabbit anti Human prolyl hydroxylase 1 antibody recognizes prolyl hydroxylase 1, also known as PHD1, EGLN2, HIF-prolyl hydroxylase 1, egl9 homolog 2, hypoxia-inducible factor prolyl hydroxylase 1 and prolyl hydroxylase domain-containing protein 1. Hypoxia inducible factor (HIF) is a transcriptional complex that is involved in oxygen homeostasis.

Inhibition of prolyl hydroxylase 3 ameliorates cardiac anti hif prolyl hydroxylases polyclonal primary antibodies

Prolyl hydroxylase 3 (PHD3) is a member of the prolyl hydroxylases (PHDs) family and is induced by hypoxia. It plays a critical role in regulating the abundance of hypoxia-inducible factor (HIF). Its expression is increased in diabetic rat hearts; however, its role remains unclear.Inhibition of prolyl hydroxylase 3 ameliorates cardiac anti hif prolyl hydroxylases polyclonal primary antibodiesProlyl hydroxylase 3 (PHD3) is a member of the prolyl hydroxylases (PHDs) family and is induced by hypoxia. It plays a critical role in regulating the abundance of hypoxia-inducible factor (HIF). Its expression is increased in diabetic rat hearts; however, its role remains unclear.Intrabody against prolyl hydroxylase 2 promotes anti hif prolyl hydroxylases polyclonal primary antibodiesAug 14, 2019Hypoxia-inducible factor (HIF)-1 is a crucial transcription factor that regulates the expression of target genes involved in angiogenesis. Prolyl hydroxylase 2 (PHD2) dominantly hydroxylates two anti hif prolyl hydroxylases polyclonal primary antibodies

Intrabody against prolyl hydroxylase 2 promotes anti hif prolyl hydroxylases polyclonal primary antibodies

Aug 14, 2019Hypoxia-inducible factor (HIF)-1 is a crucial transcription factor that regulates the expression of target genes involved in angiogenesis. Prolyl hydroxylase 2 (PHD2) dominantly hydroxylates two anti hif prolyl hydroxylases polyclonal primary antibodiesLoss of HIF-1 impairs GLUT4 translocation and glucose anti hif prolyl hydroxylases polyclonal primary antibodiesThe hypoxia-inducible factor (HIF)-1 is a heterodimeric anti hif prolyl hydroxylases polyclonal primary antibodies nated HIF prolyl hydroxylases. The hypoxic condition de- anti hif prolyl hydroxylases polyclonal primary antibodies Anti-HIF-1 hydroxy P564 rabbit polyclonal antibody was from Rockland (Gilbertsville, PA). Mouse monoclonal anti- -tubulin antibody was from Upstate Biotechnology (Lake Placid, NY).Original Article Prolyl Hydroxylase-2 (PHD2) Exerts bation with primary antibodies. PHD2 and HIF-1a anti-bodies (1:1000 dilution; Novus Biologicals, Cambridge, United Kingdom) were incubated at 4 C overnight. The membranes then were washed in TBS-T and incubated with horseradish peroxidase-conjugated secondary anti-bodies (Amersham Life Science, Buchinghamshire,

Original Article Prolyl Hydroxylase-2 (PHD2) Exerts

bation with primary antibodies. PHD2 and HIF-1a anti-bodies (1:1000 dilution; Novus Biologicals, Cambridge, United Kingdom) were incubated at 4 C overnight. The membranes then were washed in TBS-T and incubated with horseradish peroxidase-conjugated secondary anti-bodies (Amersham Life Science, Buchinghamshire,PHD1 Rabbit anti-Human, Polyclonal, Bioss 100 µL anti hif prolyl hydroxylases polyclonal primary antibodiesThe prolyl hydroxylases catalyze the posttranslational formation of 4-hydroxyproline in HIF-alpha proteins. HIF PHD1, which is widely expressed, with highest levels of expression in testis, functions as a cellular oxygen sensor and is important in cell growth regulation.Product_HuaBio-Antibodies Reagents Custom antibody anti hif prolyl hydroxylases polyclonal primary antibodiesThe prolyl hydroxylases catalyze the posttranslational formation of 4-hydroxyproline in HIF- proteins. HIF PHD1, which is widely expressed, with highest levels of expression in testis, functions as a cellular oxygen sensor and is important in cell growth regulation.

Prolyl 4-Hydroxylase, Transmembrane anti hif prolyl hydroxylases polyclonal primary antibodies - Antibodies

The product of this gene belongs to the family of prolyl 4-hydroxylases. This protein is a prolyl hydroxylase that may be involved in the degradation of hypoxia Prolyl hydroxylase2 (PHD2) exerts tumorsuppressive anti hif prolyl hydroxylases polyclonal primary antibodiesJul 26, 2011Membranes were then incubated in blocking solution (5% nonfat milk in 20 mM Tris/Cl, 150 mM NaCl, and 0.1% Tween20 [TBST]), followed by incubation with primary antibodies. PHD2 and HIF1 antibodies (1:1000 dilution; Novus Biologicals, Cambridge, United Kingdom) were incubated at 4°C overnight. The membranes then were washed in TBS anti hif prolyl hydroxylases polyclonal primary antibodiesRelated searches for anti hif prolyl hydroxylases polyclonal hypoxia inducible factor prolyl hydroxylaseprolyl hydroxylase inhibitorprolyl 4 hydroxylases definitionprolyl hydroxylationhydroxylase inhibitorsAnti-PHD1 Antibodies InvitrogenPHD1 Antibodies . Prolyl hydroxylase domain proteins HIF PHD1, HIF PHD2 and HIF PHD3 (known as PHD1, PHD2 and PHD3 in rodents, respectively) can hydroxylate HIF-alpha subunits. Hypoxia-inducible factor (HIF) is a transcriptional regulator important in several aspects of oxygen homeostasis.

Results for "Prolyl Hydroxylase" Abcam antibodies anti hif prolyl hydroxylases polyclonal primary antibodies

Anti-HIF Prolyl Hydroxylases antibody [EPR3664(2)-25] - BSA and Azide free (ab256316) Description Rabbit monoclonal [EPR3664(2)-25] to HIF Prolyl Hydroxylases - BSA and Azide freeThe prolyl 3-hydroxylases P3H2 and P3H3 are novel targets anti hif prolyl hydroxylases polyclonal primary antibodiesMay 12, 2009The prolyl 3-hydroxylases P3H2 and P3H3 are novel targets for epigenetic silencing in breast cancer anti hif prolyl hydroxylases polyclonal primary antibodies membrane that were incubated for 1 h with primary antibodies. anti hif prolyl hydroxylases polyclonal primary antibodies of prolyl-4-hydroxylases anti hif prolyl hydroxylases polyclonal primary antibodiesThe prolyl 3-hydroxylases P3H2 and P3H3 are novel targets anti hif prolyl hydroxylases polyclonal primary antibodiesMay 12, 2009The prolyl 3-hydroxylases P3H2 and P3H3 are novel targets for epigenetic silencing in breast cancer anti hif prolyl hydroxylases polyclonal primary antibodies membrane that were incubated for 1 h with primary antibodies. anti hif prolyl hydroxylases polyclonal primary antibodies of prolyl-4-hydroxylases anti hif prolyl hydroxylases polyclonal primary antibodies

anti-Homo sapiens (Human) EGLN1 Antibody raised in

Data show that dimethyl-2-ketoglutarate (DKG) inhibits hypoxia-inducible factor 1alpha (HIF-1alpha) proline hydroxylation and degradation mediated by prolyl-4-hydroxylase PHD2. PMID 25420025 striking enrichment of high-altitude ancestry in the Tibetan genome, indicating that migrants from low altitude acquired adaptive alleles from the anti hif prolyl hydroxylases polyclonal primary antibodiesanti-Homo sapiens (Human) EGLN1 Antibody raised in Data show that dimethyl-2-ketoglutarate (DKG) inhibits hypoxia-inducible factor 1alpha (HIF-1alpha) proline hydroxylation and degradation mediated by prolyl-4-hydroxylase PHD2. PMID 25420025 striking enrichment of high-altitude ancestry in the Tibetan genome, indicating that migrants from low altitude acquired adaptive alleles from the anti hif prolyl hydroxylases polyclonal primary antibodiesanti-Prolyl 4-Hydroxylase anti hif prolyl hydroxylases polyclonal primary antibodies - antibodies-onlineThe product of this gene belongs to the family of prolyl 4-hydroxylases. This protein is a prolyl hydroxylase that may be involved in the degradation of hypoxia-inducible transcription factors under normoxia. It plays a role in adaptation to hypoxia and may be related to cellular oxygen sensing.